CHEPON2024

15th International Meeting on Cholinesterases and 9th International Meeting on Paraoxonases

banner

CHEPON2024 :: Electronic Program

Calendar
Program by Tracks Program by Sessions
Sign in to read full abstracts

Warning! Current (By Session) view only lists sessions containing presentations

If you want to see the entire program (including events not backed by paper submissions), please choose the "Program by Tracks" view instead (see buttons above).

How to use the calendar

The week-view displays short versions of session names in case there are multiple parallel tracks. To view the full name of a particular track/session, hover over with your mouse to display the tooltip.
If you wish to view the names of the sessions written out in full regardless of whether they are in parallel tracks or not, switch to the day view using the header bar of the calendar (immediately below this message).

Index
Program by Tracks Program by Sessions

Warning! Current (By Session) view only lists sessions containing presentations

If you want to see the entire program (including events not backed by paper submissions), please choose the "Program by Tracks" view instead (see buttons above).

Program Index by Sessions

Sunday - Opening Session
Wednesday - Memorial Lecture
Wednesday - Closing Lecture

Monday - Morning Lectures

Monday - Late morning Lectures

Monday - Afternoon Lectures

Monday - Late afternoon Lectures

Monday - Poster Session
Tuesday - Poster Session

Tuesday - Morning Lectures

Wednesday - Morning Lectures

Wednesday - Late morning Lectures

Wednesday - Afternoon Lectures

Program Index by Tracks

Sunday

Monday

Tuesday

Wednesday
Program (by Sessions)
Program by Tracks Program by Sessions

Warning! Current (By Session) view only lists sessions containing presentations

If you want to see the entire program (including events not backed by paper submissions), please choose the "Program by Tracks" view instead (see buttons above).

Session: Plenary and other Distinguished Lectures

Track: Sunday - Opening Session

Scheduled for: Sunday, Sep 15, 2024 6:00 pm — 7:30 pm (Europe/Ljubljana)

Presentations:

(4153) A single nucleotide polymorphism in the human AChE gene alters miR-608 levels, anxiety and inflammatory status [PL-1]
Hermona Soreq, Nimrod Madrer, Yonat Tzur, Adi Bar, Estelle Bennett, Alon Simchovitz, David Greenberg
Sunday, 6:00 pm — 6:45 pm
(4409) PON1, as a common denominator of neurodegenerative and cardiovascular diseases: proactive player or static biomarker? [PL-2]
Carlo Cervellati, Raffealla Riccetti, Gianmarco Mola, Valentina Rosta, Alessandro Trentini
Sunday, 6:45 pm — 7:30 pm

Track: Wednesday - Memorial Lecture

Scheduled for: Wednesday, Sep 18, 2024 4:00 pm — 4:30 pm (Europe/Ljubljana)

Presentations:

(4711) Memorial Lecture [PL-3]
Eugenio Vilanova
Wednesday, 4:00 pm — 4:25 pm

Track: Wednesday - Closing Lecture

Scheduled for: Wednesday, Sep 18, 2024 4:30 pm — 5:15 pm (Europe/Ljubljana)

Presentations:

(4511) Structural Characterization of Orphan and Taxonomically Restricted Proteins [PL-4]
Israel Silman
Wednesday, 4:30 pm — 5:15 pm

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Session: Session I - Structure and dynamics of cholinesterases, paraoxonases and phosphotriesterases

Track: Monday - Morning Lectures

Scheduled for: Monday, Sep 16, 2024 8:30 am — 10:20 am (Europe/Ljubljana)

Presentations:

(4562) An Unusual α/β Hydrolase Fold Enzyme from an Antarctic Bacterium [KN-01]
Joel L. Sussman
Monday, 8:30 am — 9:00 am
(4496) Phosphotriesterase catalyzed synthesis of chiral precursors to antiviral prodrugs [OR-01]
Frank Raushel
Monday, 9:00 am — 9:20 am
(4300) Disentangling the mechanism underlying the covalent MSF-AChE adduct formation and evolvement: mechanistic insights into an aged-like inactive complex susceptible to reactivation by a combination of nucleophiles [OR-02]
Jure Stojan, Alessandro Pesaresi, Anže Meden, Doriano Lamba
Monday, 9:20 am — 9:40 am
(4454) Acetylcholinesterase dynamics determine the potency and selectivity of inhibitors targeting disease-transmitting mosquitoes [OR-03]
Anna Linusson Jonsson, Rashmi Kumari, Cecilia Lindgren, Rajendra Kumari, Nina Forsgren, David Andersson, Fredrik Ekström
Monday, 9:40 am — 10:00 am
(4305) Structure and dynamics of hAChE and oxime interactions in structure-based design of novel uncharged bis-oxime reactivators [OR-04]
Andrey Kovalevsky, Oksana Gerlits, Thibault Alle, Carlo Ballatore, Zoran Radic
Monday, 10:00 am — 10:20 am

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Session: Session II - Interactions of cholinesterases (AChE and BChE) with substrates, inhibitors and reactivators

Track: Monday - Late morning Lectures

Scheduled for: Monday, Sep 16, 2024 10:45 am — 12:35 pm (Europe/Ljubljana)

Presentations:

(4315) Evaluating cholinesterase's interactions with inhibitors and potent reactivators towards efficient treatment in organophosphate poisoning [KN-02]
Zrinka Kovarik, Dora Kolić, Tena Cadez, Goran Šinko, Nikolina Maček Hrvat
Monday, 10:45 am — 11:15 am
(4419) Towards the fourth generation of effective uncharged bis-oxime reactivators of organophosphate-inhibited human AChE. [OR-05]
Andrey Kovalevsky, Thibault Alle, Oksana Gerlits, Nikolina Maček Hrvat, Carlo Ballatore, Zrinka Kovarik, Zoran Radic
Monday, 11:15 am — 11:35 am
(4379) Development and therapeutic potential of uncharged cholinesterase reactivators [OR-06]
José Dias, Ludovic Jean, André-Guilhem Calas, Nicolas Probst, Julien De Sousa, Nicolas Lamassiaude, Christophe Landry, Ophélie Da Silva, Anissa Braiki, Camille Voros, Romulo Araoz, Caroline Coisne, Charlotte Courageux, Pierre Warnault, Franck Razafindrainibe, Anne-Julie Gastellier, Julien Gasnot, Yerri Jagadeesh, Marilène Trancart, Anne-Sophie Hanak, Fabien Gosselet, Xavier Brazzolotto, Marie-Pierre Dehouck, Florian Nachon, Denis Servent, Pierre-Yves Renard, Rachid Baati
Monday, 11:35 am — 11:55 am
(4574) Direct Determination of the hydrolysis of a poor substrate by human plasma [OR-07]
Jure Stojan
Monday, 11:55 am — 12:15 pm
(4330) Inhibition of human butyrylcholinesterase by A-series nerve agents, functional and structural characterization [OR-08]
Charlotte Courageux, Anne-Julie Gastellier, Milica Denic, Fabrice Modeste, Nicolas Taudon, José Dias, Florian Nachon, Xavier Brazzolotto
Monday, 12:15 pm — 12:25 pm
(4107) Inhibition kinetics of cholinesterases from various species by the organophosphate CBDP in vitro [OR-09]
Gabriele Horn, Franz Worek
Monday, 12:25 pm — 12:35 pm

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Session: Session III - Post exposure organo phosphates strategies and toxicology

Track: Monday - Afternoon Lectures

Scheduled for: Monday, Sep 16, 2024 2:00 pm — 3:50 pm (Europe/Ljubljana)

Presentations:

(4260) Novichok class of organophosphorus compounds and the efficacy of current countermeasures against A-234 [KN-03]
Ondrej Soukup, Daniel Jun
Monday, 2:00 pm — 2:30 pm
(4319) How to increase bioavailability and follow effect of charged oximes in the central nervous system? [OR-10]
Kamil Musilek, David Malinak, Eliska Prchalova, Rudolf Andrys, Adam Skarka, Zbynek Heger, Zenon Starcuk
Monday, 2:30 pm — 2:50 pm
(4389) Novel Strategies for Optimizing the Treatment of Organophosphate Poisoning in a Mouse Model [OR-11]
Marilène Trancart, Anne-Sophie Hanak, Karine Thibault, Grégory Dal Bo, Alexandre Champault, Méliati Madi, Gwladys Meesemaecker, André-Guilhem Calas
Monday, 2:50 pm — 3:10 pm
(4470) Choline-O-acetyltransferase as a potential therapeutic target for nerve agent poisoning: unveiling an ion sensitive regulatory mechanism [OR-12]
Fredrik Ekström, Nina Forsgren, Frida Jonsson, Cecilia Engdahl, Tomas Bergström
Monday, 3:10 pm — 3:30 pm
(4434) Investigation of neuroprotection conferred by a new therapeutic strategy after organophosphorus exposure [OR-13]
Alexandre Champault, Julie Knoertzer, Armelle Rancillac, Grégory Dal Bo, Karine Thibault
Monday, 3:30 pm — 3:40 pm
(4438) Blood-brain barrier controlled-opening with ultrasound to improve neuroprotection after nerve agent exposure [OR-14]
Lucie Lépinard, Sarah Leterrier, Laurène Jourdain, Karine Thibault, Anthony Novell, Grégory Dal Bo
Monday, 3:40 pm — 3:50 pm

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Session: Session IV - Cholinesterase pharmacology, inhibitors and antidotes

Track: Monday - Late afternoon Lectures

Scheduled for: Monday, Sep 16, 2024 4:15 pm — 6:05 pm (Europe/Ljubljana)

Presentations:

(4682) Balancing central and peripheral nervous system antidotal actions of oxime reactivators to acetylcholinesterase inhbition [KN-04]
Palmer Taylor, Kwok-Yiu Ho, Zoran Radic
Monday, 4:15 pm — 4:45 pm
(4515) Development of the post-exposure RS194B oxime against lethal sarin vapour and organophosphate insecticides in macaques [OR-15]
Yvonne Rosenberg, Dennis Sullivan, Zoran Radic, Palmer Taylor
Monday, 4:45 pm — 5:05 pm
(4414) Detection of selective inhibitors of BChE in structurally and functionally different groups of molecules [OR-16]
Anita Bosak, Ana Matošević, Marija Bartolić, Ines Primožič, Alma Ramić, Xavier Brazzolotto, Florian Nachon, Nikola Maraković
Monday, 5:05 pm — 5:25 pm
(4130) Bifunctional compounds serving as versatile cholinesterase reactivators [OR-17]
Lukas Gorecki, Martina Hrabinova, Vendula Hepnarova, Jana Zdarova Karasova, Jan Korabecny
Monday, 5:25 pm — 5:45 pm
(4565) Attenuating organophosphate-induced neuroinflammation in mice by oxime therapy [OR-18]
Nikolina Maček Hrvat, Katarina Ilić, Dora Kolić, Borna Puljko, Palmer Taylor, Kristina Mlinac Jerković, Svjetlana Kalanj Bognar, Zrinka Kovarik
Monday, 5:45 pm — 5:55 pm
(4459) Design and Evaluation of Acetylcholinesterase Reactivators: A study of reactive oxime- and peripheral site-moieties [OR-19]
Cecilia Springer Engdahl, Norman Hoster, Cecilia Lindgren, Nina Forsgren, Frida Jonsson, Timo Wille, Franz Worek, Anna Linusson Jonsson, Fredrik Ekström
Monday, 5:55 pm — 6:05 pm

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Session: Poster Session

Track: Monday - Poster Session

Scheduled for: Monday, Sep 16, 2024 6:05 pm — 7:30 pm (Europe/Ljubljana)

Presentations:

(4462) Target-guided synthesis of novel butyrylcholinesterase inhibitors [PO-01 / B-01]
Ines Primožič, Alma Ramić, Toni Divjak, Tomica Hrenar
Monday, 6:05 pm — 7:30 pm
(4333) Capitalizing on human BChE-ligand complex structures for the design of BChE-specific reactivator against nerve agent intoxication [PO-02 / B-02]
Damijan Knez, Masa Zorman, Anne-Julie Gastellier, Charlotte Courageux, Janek Bzdrenga, José Dias, Xavier Brazzolotto
Monday, 6:05 pm — 7:30 pm
(4402) Monoquaternary analogues of double charged K-oximes (K027, K048 and K203) are less effective reactivators of cholinesterases inhibited by organophosphates [PO-03 / B-03]
Zuzana Kohoutova, Rudolf Andrys, Kamil Musilek, David Malinak
Monday, 6:05 pm — 7:30 pm
(4403) Halogenated pralidoxime analogues are efficiently reactivating cholinesterases [PO-04 / B-04]
Sara Rademacherova, Karolina Knittelova, Adela Fuchsova, Rudolf Andrys, Kamil Musilek, David Malinak
Monday, 6:05 pm — 7:30 pm
(4404) Brominated oxime nucleophiles are efficiently reactivating cholinesterases inhibited by nerve agents [PO-05 / B-05]
Eliska Prchalova, Rudolf Andrys, Jaroslav Pejchal, Zuzana Kohoutova, Kamil Musilek, Jana Zdarova Karasova, David Malinak
Monday, 6:05 pm — 7:30 pm
(4383) Importance of the shape of the linker between two quaternary pyridinium rings on reactivation process in oximes – in vitro and in silico study [PO-06 / B-06]
Tanos Celmar Costa Franca, Fernanda Georgia Figueiredo Taborda Barbosa, Joyce Sobreiro Francisco Diz de Almeida, Eugenie Nepovimova, Rafael Dolezal, Steven Laplate, Kamil Kuca
Monday, 6:05 pm — 7:30 pm
(4426) Synthesis and in vitro assessment of the reactivation profile of clinical oximes on the acetylcholinesterase model inhibited by A-230 and A-242 nerve agents’ surrogates [PO-07 / B-07]
Tanos Celmar Costa Franca, Samir Cavalcante, Daniel Kitagawa, Caio Borges, Marcelo Carneiro dos Santos, Pedro Buitrago, Roberto Souza, Antonio Luis Santos Lima, Leandro Bernardo, Kamil Kuca
Monday, 6:05 pm — 7:30 pm
(4469) Synthesis, modeling and in vitro assessment of the reactivation profile of monocationic isatin-oximes hibrids on the acetylcholinesterase model inhibited by nerve agents’ surrogates [PO-08 / B-08]
Tanos Celmar Costa Franca, Amanda Moraes, Samir Cavalcante, Dipanjan Bhattacharyya, Steven Laplate, Joyce Sobreiro Francisco Diz de Almeida, Pat Forgione
Monday, 6:05 pm — 7:30 pm
(4486) Triazoles as potential reactivators of human acetylcholinesterase inhibited by the nerve agents VX and Novichok A-242 [PO-09 / B-09]
Fernanda Pires, Pedro Buitrago, Tanos Celmar Costa Franca, Samir Cavalcante, Joyce Sobreiro Francisco Diz de Almeida
Monday, 6:05 pm — 7:30 pm
(4601) Beyond carbamates: N-substituted piperidine ureas as butyrylcholinesterase inhibitors [PO-10 / B-10]
Peter Mastnak-Sokolov, Urban Košak, Damijan Knez, Svit Ferjančič Benetik, Anja Pišlar, Xavier Brazzolotto, Stanislav Gobec
Monday, 6:05 pm — 7:30 pm
(4045) Piperidine-carboxamides, -sulfonamides and -carbamates as selective butyrylcholinesterase inhibitors [PO-11 / B-11]
Urban Košak, Damijan Knez, Anže Meden, Simon Žakelj, Jurij Trontelj, Jure Stojan, Maja Zakošek Pipan, Kinga Sałat, Florian Nachon, Xavier Brazzolotto, Gregor Majdič, Stanislav Gobec
Monday, 6:05 pm — 7:30 pm
(4357) In vitro reactivation screening of A-234-inhibited human recombinant acetylcholinesterase and butyrylcholinesterase [PO-12 / B-12]
Martina Hrabinova
Monday, 6:05 pm — 7:30 pm
(4571) Computational investigation of hardwickic acid-derived amides using molecular docking and prediction of ADME/Tox properties as potential inhibitors of cholinesterase enzymes [PO-13 / B-13]
Rayssa Ribeiro, Franco Leite, Gessica Mendes, Fernanda Georgia Figueiredo Taborda Barbosa, Samir Cavalcante, Marcelo Carneiro dos Santos, Tanos Celmar Costa França, Valdir Veiga-Junior
Monday, 6:05 pm — 7:30 pm
(4578) Modeling studies and experimental evaluation of the reactivation potential of oximes K027, K048, K170 and K203 against the nerve agent A-242 [PO-14 / B-14]
Daniel de Jesus de Oliveira, Fernanda Diniz Botelho, Fernanda Georgia Figueiredo Taborda Barbosa, Kamil Kuca, Steven Laplate, Samir Cavalcante, Marcelo Carneiro dos Santos, Tanos Celmar Costa França
Monday, 6:05 pm — 7:30 pm
(4448) Novichok A-232: basic knowledge of biochemical and toxicological properties [PO-15 / B-15]
Daniel Jun, Martina Hrabinova, Lubica Muckova, Jakub Opravil, Dominik Krupka, Alzbeta Dlabkova
Monday, 6:05 pm — 7:30 pm
(4476) Reactivation potency of GB, VX and A-234-inhibited human recombinant acetylcholinesterase in vitro and in silico [PO-16 / B-16]
Jakub Opravil, Jakub Fibigar, Zbyněk Večeřa
Monday, 6:05 pm — 7:30 pm
(4456) Exploring drug modality switch from in situ assembly to reversibility: reversible modulators of choline O-acetyltransferase activity [PO-17 / B-17]
Nina Forsgren, Frida Jonsson, Marcus Carlsson, Robin Afshin Sander, Cecilia Springer Engdahl, Daniel Wiktelius, Christopher Öberg, Fredrik Ekström
Monday, 6:05 pm — 7:30 pm
(4429) Kinetic and structural evidence for specific DMSO interference with reversible binding of uncharged bis-oximes to hAChE and their reactivation kinetics of OP-hAChE. [PO-18 / B-18]
Dora Kolić, Nichole Joiner, Oksana Gerlits, Andrey Kovalevsky, Zoran Radic
Monday, 6:05 pm — 7:30 pm
(4318) Outlining the A-series of organophosphorus compounds – cholinesterase inhibition, reactivation, cytotoxicity [PO-19 / B-19]
Nikolina Maček Hrvat, Dora Kolić, Tena Cadez, Goran Šinko, Zrinka Kovarik
Monday, 6:05 pm — 7:30 pm
(4321) Evaluation of resveratrol compounds as therapeutics in organophosphorus poisoning [PO-20 / B-20]
Tena Cadez, Milena Mlakić, Nikolina Maček Hrvat, Irena Škorić, Zrinka Kovarik
Monday, 6:05 pm — 7:30 pm
(4343) Neuroprotective role of CNS-active uncharged bis-oxime antidotes in mice exposed to organophosphate compounds [PO-21 / B-21]
Dora Kolić, Nikolina Maček Hrvat, Zrinka Kovarik, Zoran Radic
Monday, 6:05 pm — 7:30 pm
(4554) Synthesis of broad-spectrum antidotes to organophosphorus neurotoxins [PO-22 / B-22]
Estelle Beaupparain, Karine Porte, Pierre-Yves Renard, Ludovic Jean
Monday, 6:05 pm — 7:30 pm
(4474) Bis-pyridinium mono-aldoxime K203: a promising prophylactic cholinesterase reactivator for organophosphate poisoning. [PO-23 / B-23]
Syed Nurulain, Zarish Riaz, Huba Kalasz, Sajid Mehmood, Kamil Kuca
Monday, 6:05 pm — 7:30 pm
(4390) A-agents: more resistant than expected? Biomarker detection in biological matrices [PO-24 / B-24]
Lukáš Prchal, Alzbeta Dlabkova
Monday, 6:05 pm — 7:30 pm

Track: Tuesday - Poster Session

Scheduled for: Tuesday, Sep 17, 2024 11:00 am — 12:35 pm (Europe/Ljubljana)

Presentations:

(4617) PON1 gene polymorphisms and inflammatory markers in organophosphate pesticides cohorts from Cameroon and Pakistan [PO-25 / B-01]
Leonel Javeres Mbah Ntepe
Tuesday, 11:00 am — 12:35 pm
(4648) Screening and Characterization of Inhibitors for the Recombinant Variant of Paraoxonase 1 [PO-26 / B-02]
Neja Žnidaršič, Janez Smerkolj, Jure Stojan, Aljoša Bavec, Marko Goličnik
Tuesday, 11:00 am — 12:35 pm
(4583) Exploring the Impact of Lanthanide (III) Ions on the Function of Paraoxonase 1 (PON1) [PO-27 / B-03]
Janez Smerkolj, Jure Stojan, Aljoša Bavec, Marko Goličnik
Tuesday, 11:00 am — 12:35 pm
(4625) PON1 plasma activity in the aftermath of bariatric metabolic surgery: the benefits of investigating more than one substrate [PO-28 / B-04]
Boštjan Petrič, Aljoša Bavec, Tadeja Pintar, Živa Mesarič
Tuesday, 11:00 am — 12:35 pm
(4382) Recombinant human paraoxonase-1 variants depict hydrolyzing capabilities of A-series nerve agents in vitro [PO-29 / B-05]
Janek Bzdrenga, Prakash Khandave, Thomas Soirot, Nicolas Belverge, Nicolas Taudon, Florian Nachon, Xavier Brazzolotto, Abhay H. Pande
Tuesday, 11:00 am — 12:35 pm
(4490) Copper-dependent stereoselective hydrolysis of O-hexyl O-2,5-dichlorophenyl phosphoramidate by recombinant serum albumins [PO-30 / B-06]
Laura Ramirez Gonzalez
Tuesday, 11:00 am — 12:35 pm
(4445) Update of ESTHER, the database and server dedicated to the analysis of protein and nucleic acid sequences within the superfamily of cholinesterase relative [PO-31 / B-07]
Arnaud Chatonnet, Zhou Yu, Nicolas Roche, Pascale Marchot
Tuesday, 11:00 am — 12:35 pm
(4286) In silico evaluation of the anticholinesterase activity of triazole fungicides [PO-32 / B-08]
Goran Šinko
Tuesday, 11:00 am — 12:35 pm
(4548) Cholinesterase monitoring for nerve agent exposure [PO-33 / B-09]
Nick Coe, Jennifer Dawson, Georgia Smith, Sarah Goodchild
Tuesday, 11:00 am — 12:35 pm
(4422) Immobilization of cholinesterases on magnetic microparticles for enhanced stability and biosensing applications [PO-34 / B-10]
Rudolf Andrys, Charline Monnier, Veronika Mickova, Louise Nemery, Evica Antonijevic, Kamil Musilek, Lucie Zemanova
Tuesday, 11:00 am — 12:35 pm
(4552) Highly potent and selective butyrylcholinesterase inhibitors for cognitive improvement and neuroprotection [PO-35 / B-11]
Baichen Xiong, Zuoaoyun Song, Haopeng Sun
Tuesday, 11:00 am — 12:35 pm
(4541) Detection of butyrylcholinesterase signal peptide in human brains [PO-36 / B-12]
Jacek Jasiecki, Andrew Reid, Meghan Cash, Monika Targońska, Bartosz Wasąg, Sultan Darvesh
Tuesday, 11:00 am — 12:35 pm
(4416) Impact of Type 1 Diabetes Mellitus on Butyrylcholinesterase Expression and Activity in Rats [PO-37 / B-13]
Tibor Hodbod, Lukas Nemet, Katarina Hadova, Anna Hrabovska
Tuesday, 11:00 am — 12:35 pm
(4418) Expression of cholinesterases in rats [PO-38 / B-14]
Lukas Nemet, Tibor Hodbod, Monika Zelinová, Anna Hrabovska
Tuesday, 11:00 am — 12:35 pm
(4542) Investigating the Link between Butyrylcholinesterase and Pulmonary Vascular Disease in Rats [PO-39 / B-15]
Parsa Shafieikazerooni, Monika Zelinová, Jana Veteskova, Eva Velasova, Tibor Hodbod, Peter Krenek, Anna Hrabovska
Tuesday, 11:00 am — 12:35 pm
(4177) Acetylcholinesterase and muscarinic receptors control the ultraviolet-mediated release of melanosomes in cultured melanoma [PO-40 / B-16]
Maggie Suisui Guo, Yingjie Xia, Jiahui Wu, Xiaoyang Wang, Gary Ka Wing Yuen, Tingxia Dong, Karl Wah-Keung Tsim
Tuesday, 11:00 am — 12:35 pm
(4338) Trehalose restores the tacrine-induced endoplasmic reticulum stress in cultured neuronal cells [PO-41 / B-17]
Xiaoyang Wang, Yingjie Xia, Maggie Suisui Guo, Jiahui Wu, Tingxia Dong, Karl Wah-Keung Tsim
Tuesday, 11:00 am — 12:35 pm
(4396) The Muscarinic Acetylcholine Receptor in Dermal Papilla Cells Regulates Hair Growth [PO-42 / B-18]
Gary Ka Wing Yuen, Tingxia Dong, Daniel Ye, Ajiaikebaier Dilidaer, Karl Wah Keung Tsim
Tuesday, 11:00 am — 12:35 pm
(4407) The Regulatory Role of Gut Microbiota in Expression of AChE in Epithelial Cells: a Regulator of Inflammatory Bowel Disease [PO-43 / B-19]
Ajiaikebaier Dilidaer, Yingjie Xia, Jiahui Wu, Tingxia Dong, Karl Wah-Keung Tsim
Tuesday, 11:00 am — 12:35 pm
(4425) Studying the Expression and Regulation of AChE in Multiple Cancers Using Data-Driven Approach [PO-44 / B-20]
Jiahui An, Heidi QH Xie, Ruihong Zhu, Guanglei Yang, Yangsheng Chen, Li Xu, Bin Zhao
Tuesday, 11:00 am — 12:35 pm
(4388) Advances in the development of new drugs against Alzheimer’s disease based on tacrine scaffold [PO-45 / B-21]
Martin Novák, Vajrychova Marie, Volker M. Lauschke, Ondrej Soukup
Tuesday, 11:00 am — 12:35 pm
(4320) Synthesis of a multifunctional compound targeting neuroinflammation and cholinergic deficit in Alzheimer’s disease [PO-46 / B-22]
David Malinak, Zuzana Kohoutova, Miroslav Psotka, Karolina Knittelova, Rudolf Andrys, Kamil Musilek, Stanislav Gobec
Tuesday, 11:00 am — 12:35 pm
(4512) Dual inhibitors targeting BChE and p38α MAPK: a novel strategy for Alzheimer's disease therapy [PO-47 / B-23]
Svit Ferjančič Benetik, Aleš Obreza, Urban Košak, Damijan Knez, Stanislav Gobec
Tuesday, 11:00 am — 12:35 pm
(4475) Berberine in comparison to 7-MEOTA for Alzheimer's treatment: a polypharmacological approach [PO-48 / B-24]
Syed Nurulain, Areeba Kiran, Sidra Batool, Sosan Khan, Huba Kalasz, Sajid Mehmood, Kamil Kuca
Tuesday, 11:00 am — 12:35 pm
(4380) Novel amiridine-based multi-target directed ligands for the Alzheimer's disease treatment [PO-49 / B-25]
Jan Konecny, Eva Mezeiova, Martin Horak, Galina Makhaeva, Jan Korabecny
Tuesday, 11:00 am — 12:35 pm
(4644) Investigating the effects of basketball and volleyball as team sports on social cognitive function and BDNF and cholinesterase levels in young men and women [PO-50 / B-26]
Muslum Gok, Halil Ates, Ergul Cansu incegil, Serkan Aksu
Tuesday, 11:00 am — 12:35 pm
(4674) Design of AChE reactivators using versatile molecular platforms and nanodiamonds [PO-51 / B-27]
Yevgen Karpichev, Illia Kapitanov, Denys Bondar, Vadym Mochalin
Tuesday, 11:00 am — 12:35 pm

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Session: Session V - Paraoxonase, butyrylcholinesterase and phosphotriesterase role in detoxication, biotechnology and diseases

Track: Tuesday - Morning Lectures

Scheduled for: Tuesday, Sep 17, 2024 8:30 am — 10:30 am (Europe/Ljubljana)

Presentations:

(4463) The thin line between substrates or inhibitors: OP-enzymes interactions for biology, toxicity, diagnosis or applications. [KN-05]
Eugenio Vilanova, Cermen Estevan, Antonio Monroy-Noyola, Miguel A Sogorb, Jorge Estévez
Tuesday, 8:30 am — 9:00 am
(4624) The influence of single nucleotide polymorphisms and substrate type on individual enzyme-kinetic rate constants for human plasma PON1 [OR-20]
Boštjan Petrič, Aljoša Bavec, Marko Goličnik
Tuesday, 9:00 am — 9:20 am
(4484) Albumin-copper complex hydrolyses chiral organophosphate compounds as a true A-esterase [OR-21]
Antonio Monroy-Noyola, Laura Ramirez Gonzalez, Damianys Almenares-Lopez, Elizabeth Undiano, Eugenio Vilanova
Tuesday, 9:20 am — 9:40 am
(4386) Special behavior of cholinesterase interactions among thiocholine and phenyl carboxyl ester as substrates and inhibitors: Implication for research applications. [OR-22]
Jorge Estévez
Tuesday, 9:40 am — 10:00 am
(4441) PON-1 arylesterase activity in older patients with mild cognitive impairment, late onset Alzheimer's disease or vascular dementia [OR-23]
Gianmarco Mola, Raffaella Riccetti, Valentina Rosta, Alessandro Trentini, Carlo Cervellati
Tuesday, 10:00 am — 10:10 am
(4464) Regulatory mechanism and functional impact of post-translational modifications on human paraoxonase 2 [OR-24]
Nagendra sai kumar Achanta, Eros A. Lampitella, Maria Marone, Elena porzio, Giuliana Catara, Giuseppina Lacerra, Giuseppe Manco
Tuesday, 10:10 am — 10:20 am
(4400) Validation and application of two AChE-targeted environmental neurotoxic pollutants detection systems [OR-25]
Ruihong Zhu, Jiahui An, Heidi QH Xie, Antonio Zandona, Tena Cadez, Zrinka Kovarik, Yangsheng Chen, Li Xu, Bin Zhao
Tuesday, 10:20 am — 10:30 am

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Session: Session VI - Translational research of inhibitors of cholinesterases and paraoxonases

Track: Wednesday - Morning Lectures

Scheduled for: Wednesday, Sep 18, 2024 8:30 am — 10:20 am (Europe/Ljubljana)

Presentations:

(4522) Pharmaceutical development of plasma butyrylcholinesterase: a breakthrough in the treatment of nerve agent intoxications [KN-06]
Florian Nachon, Anne Christine Mendes, Aurélie Nervo, Xavier Brazzolotto, Chloé Reymond, Nicolas Doisne, Moussa Kenawi, Janek Bzdrenga, Fabien Chantegreil, Méliati Madi, Thomas Soirot, Nicolas Taudon, Nicolas Belverge, Aurelie Servonnet, Fanny Magisson, Nina Jaffré, Julien Bouix, Rachel Haus, Catherine Verret, Frédéric Dorandeu
Wednesday, 8:30 am — 9:00 am
(4437) Selective butyrylcholinesterase inhibition induces antidepressant, pro-cognitive, and antianhedonic effects in a genetic animal model of depression: Role of acetylcholine, ghrelin, and dopamine [OR-26]
Brian Harvey, Nadia Olivier, Stanislav Gobec, Mohammed Shahid, Urban Košak, Simon Žakelj, Christiaan Brink
Wednesday, 9:00 am — 9:20 am
(4302) Leveraging template effects of acetylcholinesterase for the development of new anti-Alzheimer drug candidates with multiple mechanisms [OR-27]
Anna Sampietro, Wawrzyniec Haberek, Aina Bellver, Christian Griñán-Ferré, Belén Pérez, Carmen Pérez de la Lastra Aranda, Valle Palomo, Marina Naldi, Manuela Bartolini, María Isabel Loza, José Brea, Clara Bartra, Coral Sanfeliu, Christophe Morisseau, Raimon Sabate, Beste Ozaydin, Jordi Juárez-Jiménez, Bruce D. Hammock, Mercè Pallàs, Santiago Vázquez, Diego Muñoz-Torrero
Wednesday, 9:20 am — 9:40 am
(4458) A novel identification of anti-hypertensive drug spironolactone as an inhibitor of paraoxonase-2 lactonase activity [OR-28]
Yoko Suzumoto, Eros A. Lampitella, Maria Marone, Giovambattista Capasso, Francesco Trepiccione, Giuseppe Manco
Wednesday, 9:40 am — 10:00 am
(4337) Development of pleiotropic prodrugs to treat Alzheimer’s disease: from conception to in vivo evaluation [OR-29]
Alice Wang, Valentin Travers--Lesage, Marc Since, Christophe Rochais
Wednesday, 10:00 am — 10:10 am
(4443) The selective butyrylcholinesterase inhibitor UW-MD-95 shows symptomatic and neuroprotective effects in a pharmacological mouse model of Alzheimer's disease [OR-30]
Allison Carles, Matthias Hoffmann, Matthias Scheiner, Lucie Crouzier, Christelle Bertrand-Gaday, Arnaud Chatonnet, Michael Decker, Tangui Maurice
Wednesday, 10:10 am — 10:20 am

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Session: Session VII - Multi-target-directed ligands in Alzheimer’s disease primarily targeting cholinesterases

Track: Wednesday - Late morning Lectures

Scheduled for: Wednesday, Sep 18, 2024 10:45 am — 12:35 pm (Europe/Ljubljana)

Presentations:

(4501) Multi-target-directed ligands for potential symptomatic and disease-modifying treatment of Alzheimer's disease [KN-07]
Svit Ferjančič Benetik, Damijan Knez, Urban Košak, Aleš Obreza, Stanislav Gobec
Wednesday, 10:45 am — 11:15 am
(4602) Advancing neocopride: a preclinical candidate multitarget directed-ligand (MTDL) for neurodegenerative disease intervention [OR-31]
Christophe Rochais, Patrick Dallemagne
Wednesday, 11:15 am — 11:35 am
(4549) Cholinesterase-based inhibitors as multitarget small molecules for the therapy of Alzheimer’s disease [OR-32]
José Marco Contelles, Francisco López-Muñoz
Wednesday, 11:35 am — 11:55 am
(4539) Discovery of novel BChE inhibitors for cognitive improvement [OR-33]
Baichen Xiong, Yuanyuan Wang, Weiting Zhang, Haopeng Sun
Wednesday, 11:55 am — 12:15 pm
(4154) Development of dual pharmacophore models of acetylcholinesterase and human soluble epoxide hydrolase based on local co-solvent molecules distribution [OR-34]
Weronika Bagrowska, Artur Góra
Wednesday, 12:15 pm — 12:25 pm
(4406) Pleiotropic prodrugs for both symptomatic and disease-modifying treatment of Alzheimer’s disease [OR-35]
Anže Meden, Neža Žnidaršič, Damijan Knez, Yuanyuan Wang, Ziwei Xu, Huajing Yang, Weiting Zhang, Anja Pišlar, Andrej Perdih, Simona Kranjc Brezar, Neža Grgurevič, Stane Pajk, Haopeng Sun, Stanislav Gobec
Wednesday, 12:25 pm — 12:35 pm

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Session: Session VIII - Functions of cholinesterases in different tissues

Track: Wednesday - Afternoon Lectures

Scheduled for: Wednesday, Sep 18, 2024 2:00 pm — 4:00 pm (Europe/Ljubljana)

Presentations:

(4427) Acetylcholinesterase regulates inflammatory responses and pigmentation in skin epidermis [KN-08]
Karl Wah-Keung Tsim
Wednesday, 2:00 pm — 2:30 pm
(4354) Characterizing Cardiac and Vascular Cholinesterases: From Molecular Insights to Therapeutic Prospects [OR-36]
Dominika Dingová, Kristína Szmicseková, Matej Kučera, Lenka Bies Pivačková, Tibor Hodbod, Parsa Shafieikazerooni, Peter Křenek, Eric Krejci, Anna Hrabovska
Wednesday, 2:30 pm — 2:50 pm
(4494) Mice with inactive cholinesterases: new tools to evaluate cholinergic and non-cholinergic functions of AChE [OR-37]
Eric Krejci
Wednesday, 2:50 pm — 3:10 pm
(4405) New perspectives on the effects of dioxin-like pollutants on acetylcholinesterase [OR-38]
Heidi QH Xie, Guanglei Yang, Ruihong Zhu, Jiahui An, Yangsheng Chen, Li Xu, Bin Zhao
Wednesday, 3:10 pm — 3:30 pm
(4630) The cholinergic enigma of pigmented and Müller glial cells [OR-39]
Paul G. Layer, Gesine Bachmann, Alex Bausch, Nicola Coronato, Gopenath Thangaraj
Wednesday, 3:30 pm — 3:50 pm
(4395) Acetylcholinesterase Reliefs Beta-Amyloid Plaque Burden via Enhancing Glial Activation in the Brain of 5×FAD Mouse [OR-40]
Yingjie Xia, Xiaoyang Wang, Maggie Suisui Guo, Ran Duan, Tingxia Dong, Karl Wah-Keung Tsim
Wednesday, 3:50 pm — 4:00 pm

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Program (by Tracks)
Program by Tracks Program by Sessions

 

Track: Sunday - Opening Ceremony

Session: N/A

Scheduled for: Sunday, Sep 15, 2024 5:30 pm — 6:00 pm (Europe/Ljubljana)

Back to Calendar

 

Track: Sunday - Opening Session

Session: Plenary and other Distinguished Lectures

Scheduled for: Sunday, Sep 15, 2024 6:00 pm — 7:30 pm (Europe/Ljubljana)
Chairs: Stanislav Gobec, Jure Stojan, Aljoša Bavec and Marko Goličnik

Presentations:

(4153) A single nucleotide polymorphism in the human AChE gene alters miR-608 levels, anxiety and inflammatory status [PL-1]
Hermona Soreq, Nimrod Madrer, Yonat Tzur, Adi Bar, Estelle Bennett, Alon Simchovitz, David Greenberg
Sunday, 6:00 pm — 6:45 pm
(4409) PON1, as a common denominator of neurodegenerative and cardiovascular diseases: proactive player or static biomarker? [PL-2]
Carlo Cervellati, Raffealla Riccetti, Gianmarco Mola, Valentina Rosta, Alessandro Trentini
Sunday, 6:45 pm — 7:30 pm

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Track: Monday - Morning Lectures

Session: Session I - Structure and dynamics of cholinesterases, paraoxonases and phosphotriesterases

Scheduled for: Monday, Sep 16, 2024 8:30 am — 10:20 am (Europe/Ljubljana)
Chair: Joel L. Sussman

Presentations:

(4562) An Unusual α/β Hydrolase Fold Enzyme from an Antarctic Bacterium [KN-01]
Joel L. Sussman
Monday, 8:30 am — 9:00 am
(4496) Phosphotriesterase catalyzed synthesis of chiral precursors to antiviral prodrugs [OR-01]
Frank Raushel
Monday, 9:00 am — 9:20 am
(4300) Disentangling the mechanism underlying the covalent MSF-AChE adduct formation and evolvement: mechanistic insights into an aged-like inactive complex susceptible to reactivation by a combination of nucleophiles [OR-02]
Jure Stojan, Alessandro Pesaresi, Anže Meden, Doriano Lamba
Monday, 9:20 am — 9:40 am
(4454) Acetylcholinesterase dynamics determine the potency and selectivity of inhibitors targeting disease-transmitting mosquitoes [OR-03]
Anna Linusson Jonsson, Rashmi Kumari, Cecilia Lindgren, Rajendra Kumari, Nina Forsgren, David Andersson, Fredrik Ekström
Monday, 9:40 am — 10:00 am
(4305) Structure and dynamics of hAChE and oxime interactions in structure-based design of novel uncharged bis-oxime reactivators [OR-04]
Andrey Kovalevsky, Oksana Gerlits, Thibault Alle, Carlo Ballatore, Zoran Radic
Monday, 10:00 am — 10:20 am

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Track: Monday - Late morning Lectures

Session: Session II - Interactions of cholinesterases (AChE and BChE) with substrates, inhibitors and reactivators

Scheduled for: Monday, Sep 16, 2024 10:45 am — 12:35 pm (Europe/Ljubljana)
Chair: Zrinka Kovarik

Presentations:

(4315) Evaluating cholinesterase's interactions with inhibitors and potent reactivators towards efficient treatment in organophosphate poisoning [KN-02]
Zrinka Kovarik, Dora Kolić, Tena Cadez, Goran Šinko, Nikolina Maček Hrvat
Monday, 10:45 am — 11:15 am
(4419) Towards the fourth generation of effective uncharged bis-oxime reactivators of organophosphate-inhibited human AChE. [OR-05]
Andrey Kovalevsky, Thibault Alle, Oksana Gerlits, Nikolina Maček Hrvat, Carlo Ballatore, Zrinka Kovarik, Zoran Radic
Monday, 11:15 am — 11:35 am
(4379) Development and therapeutic potential of uncharged cholinesterase reactivators [OR-06]
José Dias, Ludovic Jean, André-Guilhem Calas, Nicolas Probst, Julien De Sousa, Nicolas Lamassiaude, Christophe Landry, Ophélie Da Silva, Anissa Braiki, Camille Voros, Romulo Araoz, Caroline Coisne, Charlotte Courageux, Pierre Warnault, Franck Razafindrainibe, Anne-Julie Gastellier, Julien Gasnot, Yerri Jagadeesh, Marilène Trancart, Anne-Sophie Hanak, Fabien Gosselet, Xavier Brazzolotto, Marie-Pierre Dehouck, Florian Nachon, Denis Servent, Pierre-Yves Renard, Rachid Baati
Monday, 11:35 am — 11:55 am
(4574) Direct Determination of the hydrolysis of a poor substrate by human plasma [OR-07]
Jure Stojan
Monday, 11:55 am — 12:15 pm
(4330) Inhibition of human butyrylcholinesterase by A-series nerve agents, functional and structural characterization [OR-08]
Charlotte Courageux, Anne-Julie Gastellier, Milica Denic, Fabrice Modeste, Nicolas Taudon, José Dias, Florian Nachon, Xavier Brazzolotto
Monday, 12:15 pm — 12:25 pm
(4107) Inhibition kinetics of cholinesterases from various species by the organophosphate CBDP in vitro [OR-09]
Gabriele Horn, Franz Worek
Monday, 12:25 pm — 12:35 pm

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Track: Monday - Afternoon Lectures

Session: Session III - Post exposure organo phosphates strategies and toxicology

Scheduled for: Monday, Sep 16, 2024 2:00 pm — 3:50 pm (Europe/Ljubljana)
Chair: Ondrej Soukup

Presentations:

(4260) Novichok class of organophosphorus compounds and the efficacy of current countermeasures against A-234 [KN-03]
Ondrej Soukup, Daniel Jun
Monday, 2:00 pm — 2:30 pm
(4319) How to increase bioavailability and follow effect of charged oximes in the central nervous system? [OR-10]
Kamil Musilek, David Malinak, Eliska Prchalova, Rudolf Andrys, Adam Skarka, Zbynek Heger, Zenon Starcuk
Monday, 2:30 pm — 2:50 pm
(4389) Novel Strategies for Optimizing the Treatment of Organophosphate Poisoning in a Mouse Model [OR-11]
Marilène Trancart, Anne-Sophie Hanak, Karine Thibault, Grégory Dal Bo, Alexandre Champault, Méliati Madi, Gwladys Meesemaecker, André-Guilhem Calas
Monday, 2:50 pm — 3:10 pm
(4470) Choline-O-acetyltransferase as a potential therapeutic target for nerve agent poisoning: unveiling an ion sensitive regulatory mechanism [OR-12]
Fredrik Ekström, Nina Forsgren, Frida Jonsson, Cecilia Engdahl, Tomas Bergström
Monday, 3:10 pm — 3:30 pm
(4434) Investigation of neuroprotection conferred by a new therapeutic strategy after organophosphorus exposure [OR-13]
Alexandre Champault, Julie Knoertzer, Armelle Rancillac, Grégory Dal Bo, Karine Thibault
Monday, 3:30 pm — 3:40 pm
(4438) Blood-brain barrier controlled-opening with ultrasound to improve neuroprotection after nerve agent exposure [OR-14]
Lucie Lépinard, Sarah Leterrier, Laurène Jourdain, Karine Thibault, Anthony Novell, Grégory Dal Bo
Monday, 3:40 pm — 3:50 pm

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Track: Monday - Late afternoon Lectures

Session: Session IV - Cholinesterase pharmacology, inhibitors and antidotes

Scheduled for: Monday, Sep 16, 2024 4:15 pm — 6:05 pm (Europe/Ljubljana)
Chair: Palmer Taylor

Presentations:

(4682) Balancing central and peripheral nervous system antidotal actions of oxime reactivators to acetylcholinesterase inhbition [KN-04]
Palmer Taylor, Kwok-Yiu Ho, Zoran Radic
Monday, 4:15 pm — 4:45 pm
(4515) Development of the post-exposure RS194B oxime against lethal sarin vapour and organophosphate insecticides in macaques [OR-15]
Yvonne Rosenberg, Dennis Sullivan, Zoran Radic, Palmer Taylor
Monday, 4:45 pm — 5:05 pm
(4414) Detection of selective inhibitors of BChE in structurally and functionally different groups of molecules [OR-16]
Anita Bosak, Ana Matošević, Marija Bartolić, Ines Primožič, Alma Ramić, Xavier Brazzolotto, Florian Nachon, Nikola Maraković
Monday, 5:05 pm — 5:25 pm
(4130) Bifunctional compounds serving as versatile cholinesterase reactivators [OR-17]
Lukas Gorecki, Martina Hrabinova, Vendula Hepnarova, Jana Zdarova Karasova, Jan Korabecny
Monday, 5:25 pm — 5:45 pm
(4565) Attenuating organophosphate-induced neuroinflammation in mice by oxime therapy [OR-18]
Nikolina Maček Hrvat, Katarina Ilić, Dora Kolić, Borna Puljko, Palmer Taylor, Kristina Mlinac Jerković, Svjetlana Kalanj Bognar, Zrinka Kovarik
Monday, 5:45 pm — 5:55 pm
(4459) Design and Evaluation of Acetylcholinesterase Reactivators: A study of reactive oxime- and peripheral site-moieties [OR-19]
Cecilia Springer Engdahl, Norman Hoster, Cecilia Lindgren, Nina Forsgren, Frida Jonsson, Timo Wille, Franz Worek, Anna Linusson Jonsson, Fredrik Ekström
Monday, 5:55 pm — 6:05 pm

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Track: Monday - Poster Session

Session: Poster Session

Scheduled for: Monday, Sep 16, 2024 6:05 pm — 7:30 pm (Europe/Ljubljana)

Presentations:

(4462) Target-guided synthesis of novel butyrylcholinesterase inhibitors [PO-01 / B-01]
Ines Primožič, Alma Ramić, Toni Divjak, Tomica Hrenar
Monday, 6:05 pm — 7:30 pm
(4333) Capitalizing on human BChE-ligand complex structures for the design of BChE-specific reactivator against nerve agent intoxication [PO-02 / B-02]
Damijan Knez, Masa Zorman, Anne-Julie Gastellier, Charlotte Courageux, Janek Bzdrenga, José Dias, Xavier Brazzolotto
Monday, 6:05 pm — 7:30 pm
(4402) Monoquaternary analogues of double charged K-oximes (K027, K048 and K203) are less effective reactivators of cholinesterases inhibited by organophosphates [PO-03 / B-03]
Zuzana Kohoutova, Rudolf Andrys, Kamil Musilek, David Malinak
Monday, 6:05 pm — 7:30 pm
(4403) Halogenated pralidoxime analogues are efficiently reactivating cholinesterases [PO-04 / B-04]
Sara Rademacherova, Karolina Knittelova, Adela Fuchsova, Rudolf Andrys, Kamil Musilek, David Malinak
Monday, 6:05 pm — 7:30 pm
(4404) Brominated oxime nucleophiles are efficiently reactivating cholinesterases inhibited by nerve agents [PO-05 / B-05]
Eliska Prchalova, Rudolf Andrys, Jaroslav Pejchal, Zuzana Kohoutova, Kamil Musilek, Jana Zdarova Karasova, David Malinak
Monday, 6:05 pm — 7:30 pm
(4383) Importance of the shape of the linker between two quaternary pyridinium rings on reactivation process in oximes – in vitro and in silico study [PO-06 / B-06]
Tanos Celmar Costa Franca, Fernanda Georgia Figueiredo Taborda Barbosa, Joyce Sobreiro Francisco Diz de Almeida, Eugenie Nepovimova, Rafael Dolezal, Steven Laplate, Kamil Kuca
Monday, 6:05 pm — 7:30 pm
(4426) Synthesis and in vitro assessment of the reactivation profile of clinical oximes on the acetylcholinesterase model inhibited by A-230 and A-242 nerve agents’ surrogates [PO-07 / B-07]
Tanos Celmar Costa Franca, Samir Cavalcante, Daniel Kitagawa, Caio Borges, Marcelo Carneiro dos Santos, Pedro Buitrago, Roberto Souza, Antonio Luis Santos Lima, Leandro Bernardo, Kamil Kuca
Monday, 6:05 pm — 7:30 pm
(4469) Synthesis, modeling and in vitro assessment of the reactivation profile of monocationic isatin-oximes hibrids on the acetylcholinesterase model inhibited by nerve agents’ surrogates [PO-08 / B-08]
Tanos Celmar Costa Franca, Amanda Moraes, Samir Cavalcante, Dipanjan Bhattacharyya, Steven Laplate, Joyce Sobreiro Francisco Diz de Almeida, Pat Forgione
Monday, 6:05 pm — 7:30 pm
(4486) Triazoles as potential reactivators of human acetylcholinesterase inhibited by the nerve agents VX and Novichok A-242 [PO-09 / B-09]
Fernanda Pires, Pedro Buitrago, Tanos Celmar Costa Franca, Samir Cavalcante, Joyce Sobreiro Francisco Diz de Almeida
Monday, 6:05 pm — 7:30 pm
(4601) Beyond carbamates: N-substituted piperidine ureas as butyrylcholinesterase inhibitors [PO-10 / B-10]
Peter Mastnak-Sokolov, Urban Košak, Damijan Knez, Svit Ferjančič Benetik, Anja Pišlar, Xavier Brazzolotto, Stanislav Gobec
Monday, 6:05 pm — 7:30 pm
(4045) Piperidine-carboxamides, -sulfonamides and -carbamates as selective butyrylcholinesterase inhibitors [PO-11 / B-11]
Urban Košak, Damijan Knez, Anže Meden, Simon Žakelj, Jurij Trontelj, Jure Stojan, Maja Zakošek Pipan, Kinga Sałat, Florian Nachon, Xavier Brazzolotto, Gregor Majdič, Stanislav Gobec
Monday, 6:05 pm — 7:30 pm
(4357) In vitro reactivation screening of A-234-inhibited human recombinant acetylcholinesterase and butyrylcholinesterase [PO-12 / B-12]
Martina Hrabinova
Monday, 6:05 pm — 7:30 pm
(4571) Computational investigation of hardwickic acid-derived amides using molecular docking and prediction of ADME/Tox properties as potential inhibitors of cholinesterase enzymes [PO-13 / B-13]
Rayssa Ribeiro, Franco Leite, Gessica Mendes, Fernanda Georgia Figueiredo Taborda Barbosa, Samir Cavalcante, Marcelo Carneiro dos Santos, Tanos Celmar Costa França, Valdir Veiga-Junior
Monday, 6:05 pm — 7:30 pm
(4578) Modeling studies and experimental evaluation of the reactivation potential of oximes K027, K048, K170 and K203 against the nerve agent A-242 [PO-14 / B-14]
Daniel de Jesus de Oliveira, Fernanda Diniz Botelho, Fernanda Georgia Figueiredo Taborda Barbosa, Kamil Kuca, Steven Laplate, Samir Cavalcante, Marcelo Carneiro dos Santos, Tanos Celmar Costa França
Monday, 6:05 pm — 7:30 pm
(4448) Novichok A-232: basic knowledge of biochemical and toxicological properties [PO-15 / B-15]
Daniel Jun, Martina Hrabinova, Lubica Muckova, Jakub Opravil, Dominik Krupka, Alzbeta Dlabkova
Monday, 6:05 pm — 7:30 pm
(4476) Reactivation potency of GB, VX and A-234-inhibited human recombinant acetylcholinesterase in vitro and in silico [PO-16 / B-16]
Jakub Opravil, Jakub Fibigar, Zbyněk Večeřa
Monday, 6:05 pm — 7:30 pm
(4456) Exploring drug modality switch from in situ assembly to reversibility: reversible modulators of choline O-acetyltransferase activity [PO-17 / B-17]
Nina Forsgren, Frida Jonsson, Marcus Carlsson, Robin Afshin Sander, Cecilia Springer Engdahl, Daniel Wiktelius, Christopher Öberg, Fredrik Ekström
Monday, 6:05 pm — 7:30 pm
(4429) Kinetic and structural evidence for specific DMSO interference with reversible binding of uncharged bis-oximes to hAChE and their reactivation kinetics of OP-hAChE. [PO-18 / B-18]
Dora Kolić, Nichole Joiner, Oksana Gerlits, Andrey Kovalevsky, Zoran Radic
Monday, 6:05 pm — 7:30 pm
(4318) Outlining the A-series of organophosphorus compounds – cholinesterase inhibition, reactivation, cytotoxicity [PO-19 / B-19]
Nikolina Maček Hrvat, Dora Kolić, Tena Cadez, Goran Šinko, Zrinka Kovarik
Monday, 6:05 pm — 7:30 pm
(4321) Evaluation of resveratrol compounds as therapeutics in organophosphorus poisoning [PO-20 / B-20]
Tena Cadez, Milena Mlakić, Nikolina Maček Hrvat, Irena Škorić, Zrinka Kovarik
Monday, 6:05 pm — 7:30 pm
(4343) Neuroprotective role of CNS-active uncharged bis-oxime antidotes in mice exposed to organophosphate compounds [PO-21 / B-21]
Dora Kolić, Nikolina Maček Hrvat, Zrinka Kovarik, Zoran Radic
Monday, 6:05 pm — 7:30 pm
(4554) Synthesis of broad-spectrum antidotes to organophosphorus neurotoxins [PO-22 / B-22]
Estelle Beaupparain, Karine Porte, Pierre-Yves Renard, Ludovic Jean
Monday, 6:05 pm — 7:30 pm
(4474) Bis-pyridinium mono-aldoxime K203: a promising prophylactic cholinesterase reactivator for organophosphate poisoning. [PO-23 / B-23]
Syed Nurulain, Zarish Riaz, Huba Kalasz, Sajid Mehmood, Kamil Kuca
Monday, 6:05 pm — 7:30 pm
(4390) A-agents: more resistant than expected? Biomarker detection in biological matrices [PO-24 / B-24]
Lukáš Prchal, Alzbeta Dlabkova
Monday, 6:05 pm — 7:30 pm

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Track: Tuesday - Morning Lectures

Session: Session V - Paraoxonase, butyrylcholinesterase and phosphotriesterase role in detoxication, biotechnology and diseases

Scheduled for: Tuesday, Sep 17, 2024 8:30 am — 10:30 am (Europe/Ljubljana)
Chair: Eugenio Vilanova

Presentations:

(4463) The thin line between substrates or inhibitors: OP-enzymes interactions for biology, toxicity, diagnosis or applications. [KN-05]
Eugenio Vilanova, Cermen Estevan, Antonio Monroy-Noyola, Miguel A Sogorb, Jorge Estévez
Tuesday, 8:30 am — 9:00 am
(4624) The influence of single nucleotide polymorphisms and substrate type on individual enzyme-kinetic rate constants for human plasma PON1 [OR-20]
Boštjan Petrič, Aljoša Bavec, Marko Goličnik
Tuesday, 9:00 am — 9:20 am
(4484) Albumin-copper complex hydrolyses chiral organophosphate compounds as a true A-esterase [OR-21]
Antonio Monroy-Noyola, Laura Ramirez Gonzalez, Damianys Almenares-Lopez, Elizabeth Undiano, Eugenio Vilanova
Tuesday, 9:20 am — 9:40 am
(4386) Special behavior of cholinesterase interactions among thiocholine and phenyl carboxyl ester as substrates and inhibitors: Implication for research applications. [OR-22]
Jorge Estévez
Tuesday, 9:40 am — 10:00 am
(4441) PON-1 arylesterase activity in older patients with mild cognitive impairment, late onset Alzheimer's disease or vascular dementia [OR-23]
Gianmarco Mola, Raffaella Riccetti, Valentina Rosta, Alessandro Trentini, Carlo Cervellati
Tuesday, 10:00 am — 10:10 am
(4464) Regulatory mechanism and functional impact of post-translational modifications on human paraoxonase 2 [OR-24]
Nagendra sai kumar Achanta, Eros A. Lampitella, Maria Marone, Elena porzio, Giuliana Catara, Giuseppina Lacerra, Giuseppe Manco
Tuesday, 10:10 am — 10:20 am
(4400) Validation and application of two AChE-targeted environmental neurotoxic pollutants detection systems [OR-25]
Ruihong Zhu, Jiahui An, Heidi QH Xie, Antonio Zandona, Tena Cadez, Zrinka Kovarik, Yangsheng Chen, Li Xu, Bin Zhao
Tuesday, 10:20 am — 10:30 am

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Track: Tuesday - Poster Session

Session: Poster Session

Scheduled for: Tuesday, Sep 17, 2024 11:00 am — 12:35 pm (Europe/Ljubljana)

Presentations:

(4617) PON1 gene polymorphisms and inflammatory markers in organophosphate pesticides cohorts from Cameroon and Pakistan [PO-25 / B-01]
Leonel Javeres Mbah Ntepe
Tuesday, 11:00 am — 12:35 pm
(4648) Screening and Characterization of Inhibitors for the Recombinant Variant of Paraoxonase 1 [PO-26 / B-02]
Neja Žnidaršič, Janez Smerkolj, Jure Stojan, Aljoša Bavec, Marko Goličnik
Tuesday, 11:00 am — 12:35 pm
(4583) Exploring the Impact of Lanthanide (III) Ions on the Function of Paraoxonase 1 (PON1) [PO-27 / B-03]
Janez Smerkolj, Jure Stojan, Aljoša Bavec, Marko Goličnik
Tuesday, 11:00 am — 12:35 pm
(4625) PON1 plasma activity in the aftermath of bariatric metabolic surgery: the benefits of investigating more than one substrate [PO-28 / B-04]
Boštjan Petrič, Aljoša Bavec, Tadeja Pintar, Živa Mesarič
Tuesday, 11:00 am — 12:35 pm
(4382) Recombinant human paraoxonase-1 variants depict hydrolyzing capabilities of A-series nerve agents in vitro [PO-29 / B-05]
Janek Bzdrenga, Prakash Khandave, Thomas Soirot, Nicolas Belverge, Nicolas Taudon, Florian Nachon, Xavier Brazzolotto, Abhay H. Pande
Tuesday, 11:00 am — 12:35 pm
(4490) Copper-dependent stereoselective hydrolysis of O-hexyl O-2,5-dichlorophenyl phosphoramidate by recombinant serum albumins [PO-30 / B-06]
Laura Ramirez Gonzalez
Tuesday, 11:00 am — 12:35 pm
(4445) Update of ESTHER, the database and server dedicated to the analysis of protein and nucleic acid sequences within the superfamily of cholinesterase relative [PO-31 / B-07]
Arnaud Chatonnet, Zhou Yu, Nicolas Roche, Pascale Marchot
Tuesday, 11:00 am — 12:35 pm
(4286) In silico evaluation of the anticholinesterase activity of triazole fungicides [PO-32 / B-08]
Goran Šinko
Tuesday, 11:00 am — 12:35 pm
(4548) Cholinesterase monitoring for nerve agent exposure [PO-33 / B-09]
Nick Coe, Jennifer Dawson, Georgia Smith, Sarah Goodchild
Tuesday, 11:00 am — 12:35 pm
(4422) Immobilization of cholinesterases on magnetic microparticles for enhanced stability and biosensing applications [PO-34 / B-10]
Rudolf Andrys, Charline Monnier, Veronika Mickova, Louise Nemery, Evica Antonijevic, Kamil Musilek, Lucie Zemanova
Tuesday, 11:00 am — 12:35 pm
(4552) Highly potent and selective butyrylcholinesterase inhibitors for cognitive improvement and neuroprotection [PO-35 / B-11]
Baichen Xiong, Zuoaoyun Song, Haopeng Sun
Tuesday, 11:00 am — 12:35 pm
(4541) Detection of butyrylcholinesterase signal peptide in human brains [PO-36 / B-12]
Jacek Jasiecki, Andrew Reid, Meghan Cash, Monika Targońska, Bartosz Wasąg, Sultan Darvesh
Tuesday, 11:00 am — 12:35 pm
(4416) Impact of Type 1 Diabetes Mellitus on Butyrylcholinesterase Expression and Activity in Rats [PO-37 / B-13]
Tibor Hodbod, Lukas Nemet, Katarina Hadova, Anna Hrabovska
Tuesday, 11:00 am — 12:35 pm
(4418) Expression of cholinesterases in rats [PO-38 / B-14]
Lukas Nemet, Tibor Hodbod, Monika Zelinová, Anna Hrabovska
Tuesday, 11:00 am — 12:35 pm
(4542) Investigating the Link between Butyrylcholinesterase and Pulmonary Vascular Disease in Rats [PO-39 / B-15]
Parsa Shafieikazerooni, Monika Zelinová, Jana Veteskova, Eva Velasova, Tibor Hodbod, Peter Krenek, Anna Hrabovska
Tuesday, 11:00 am — 12:35 pm
(4177) Acetylcholinesterase and muscarinic receptors control the ultraviolet-mediated release of melanosomes in cultured melanoma [PO-40 / B-16]
Maggie Suisui Guo, Yingjie Xia, Jiahui Wu, Xiaoyang Wang, Gary Ka Wing Yuen, Tingxia Dong, Karl Wah-Keung Tsim
Tuesday, 11:00 am — 12:35 pm
(4338) Trehalose restores the tacrine-induced endoplasmic reticulum stress in cultured neuronal cells [PO-41 / B-17]
Xiaoyang Wang, Yingjie Xia, Maggie Suisui Guo, Jiahui Wu, Tingxia Dong, Karl Wah-Keung Tsim
Tuesday, 11:00 am — 12:35 pm
(4396) The Muscarinic Acetylcholine Receptor in Dermal Papilla Cells Regulates Hair Growth [PO-42 / B-18]
Gary Ka Wing Yuen, Tingxia Dong, Daniel Ye, Ajiaikebaier Dilidaer, Karl Wah Keung Tsim
Tuesday, 11:00 am — 12:35 pm
(4407) The Regulatory Role of Gut Microbiota in Expression of AChE in Epithelial Cells: a Regulator of Inflammatory Bowel Disease [PO-43 / B-19]
Ajiaikebaier Dilidaer, Yingjie Xia, Jiahui Wu, Tingxia Dong, Karl Wah-Keung Tsim
Tuesday, 11:00 am — 12:35 pm
(4425) Studying the Expression and Regulation of AChE in Multiple Cancers Using Data-Driven Approach [PO-44 / B-20]
Jiahui An, Heidi QH Xie, Ruihong Zhu, Guanglei Yang, Yangsheng Chen, Li Xu, Bin Zhao
Tuesday, 11:00 am — 12:35 pm
(4388) Advances in the development of new drugs against Alzheimer’s disease based on tacrine scaffold [PO-45 / B-21]
Martin Novák, Vajrychova Marie, Volker M. Lauschke, Ondrej Soukup
Tuesday, 11:00 am — 12:35 pm
(4320) Synthesis of a multifunctional compound targeting neuroinflammation and cholinergic deficit in Alzheimer’s disease [PO-46 / B-22]
David Malinak, Zuzana Kohoutova, Miroslav Psotka, Karolina Knittelova, Rudolf Andrys, Kamil Musilek, Stanislav Gobec
Tuesday, 11:00 am — 12:35 pm
(4512) Dual inhibitors targeting BChE and p38α MAPK: a novel strategy for Alzheimer's disease therapy [PO-47 / B-23]
Svit Ferjančič Benetik, Aleš Obreza, Urban Košak, Damijan Knez, Stanislav Gobec
Tuesday, 11:00 am — 12:35 pm
(4475) Berberine in comparison to 7-MEOTA for Alzheimer's treatment: a polypharmacological approach [PO-48 / B-24]
Syed Nurulain, Areeba Kiran, Sidra Batool, Sosan Khan, Huba Kalasz, Sajid Mehmood, Kamil Kuca
Tuesday, 11:00 am — 12:35 pm
(4380) Novel amiridine-based multi-target directed ligands for the Alzheimer's disease treatment [PO-49 / B-25]
Jan Konecny, Eva Mezeiova, Martin Horak, Galina Makhaeva, Jan Korabecny
Tuesday, 11:00 am — 12:35 pm
(4644) Investigating the effects of basketball and volleyball as team sports on social cognitive function and BDNF and cholinesterase levels in young men and women [PO-50 / B-26]
Muslum Gok, Halil Ates, Ergul Cansu incegil, Serkan Aksu
Tuesday, 11:00 am — 12:35 pm
(4674) Design of AChE reactivators using versatile molecular platforms and nanodiamonds [PO-51 / B-27]
Yevgen Karpichev, Illia Kapitanov, Denys Bondar, Vadym Mochalin
Tuesday, 11:00 am — 12:35 pm

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Track: Wednesday - Morning Lectures

Session: Session VI - Translational research of inhibitors of cholinesterases and paraoxonases

Scheduled for: Wednesday, Sep 18, 2024 8:30 am — 10:20 am (Europe/Ljubljana)
Chair: Florian Nachon

Presentations:

(4522) Pharmaceutical development of plasma butyrylcholinesterase: a breakthrough in the treatment of nerve agent intoxications [KN-06]
Florian Nachon, Anne Christine Mendes, Aurélie Nervo, Xavier Brazzolotto, Chloé Reymond, Nicolas Doisne, Moussa Kenawi, Janek Bzdrenga, Fabien Chantegreil, Méliati Madi, Thomas Soirot, Nicolas Taudon, Nicolas Belverge, Aurelie Servonnet, Fanny Magisson, Nina Jaffré, Julien Bouix, Rachel Haus, Catherine Verret, Frédéric Dorandeu
Wednesday, 8:30 am — 9:00 am
(4437) Selective butyrylcholinesterase inhibition induces antidepressant, pro-cognitive, and antianhedonic effects in a genetic animal model of depression: Role of acetylcholine, ghrelin, and dopamine [OR-26]
Brian Harvey, Nadia Olivier, Stanislav Gobec, Mohammed Shahid, Urban Košak, Simon Žakelj, Christiaan Brink
Wednesday, 9:00 am — 9:20 am
(4302) Leveraging template effects of acetylcholinesterase for the development of new anti-Alzheimer drug candidates with multiple mechanisms [OR-27]
Anna Sampietro, Wawrzyniec Haberek, Aina Bellver, Christian Griñán-Ferré, Belén Pérez, Carmen Pérez de la Lastra Aranda, Valle Palomo, Marina Naldi, Manuela Bartolini, María Isabel Loza, José Brea, Clara Bartra, Coral Sanfeliu, Christophe Morisseau, Raimon Sabate, Beste Ozaydin, Jordi Juárez-Jiménez, Bruce D. Hammock, Mercè Pallàs, Santiago Vázquez, Diego Muñoz-Torrero
Wednesday, 9:20 am — 9:40 am
(4458) A novel identification of anti-hypertensive drug spironolactone as an inhibitor of paraoxonase-2 lactonase activity [OR-28]
Yoko Suzumoto, Eros A. Lampitella, Maria Marone, Giovambattista Capasso, Francesco Trepiccione, Giuseppe Manco
Wednesday, 9:40 am — 10:00 am
(4337) Development of pleiotropic prodrugs to treat Alzheimer’s disease: from conception to in vivo evaluation [OR-29]
Alice Wang, Valentin Travers--Lesage, Marc Since, Christophe Rochais
Wednesday, 10:00 am — 10:10 am
(4443) The selective butyrylcholinesterase inhibitor UW-MD-95 shows symptomatic and neuroprotective effects in a pharmacological mouse model of Alzheimer's disease [OR-30]
Allison Carles, Matthias Hoffmann, Matthias Scheiner, Lucie Crouzier, Christelle Bertrand-Gaday, Arnaud Chatonnet, Michael Decker, Tangui Maurice
Wednesday, 10:10 am — 10:20 am

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Track: Wednesday - Late morning Lectures

Session: Session VII - Multi-target-directed ligands in Alzheimer’s disease primarily targeting cholinesterases

Scheduled for: Wednesday, Sep 18, 2024 10:45 am — 12:35 pm (Europe/Ljubljana)
Chair: Stanislav Gobec

Presentations:

(4501) Multi-target-directed ligands for potential symptomatic and disease-modifying treatment of Alzheimer's disease [KN-07]
Svit Ferjančič Benetik, Damijan Knez, Urban Košak, Aleš Obreza, Stanislav Gobec
Wednesday, 10:45 am — 11:15 am
(4602) Advancing neocopride: a preclinical candidate multitarget directed-ligand (MTDL) for neurodegenerative disease intervention [OR-31]
Christophe Rochais, Patrick Dallemagne
Wednesday, 11:15 am — 11:35 am
(4549) Cholinesterase-based inhibitors as multitarget small molecules for the therapy of Alzheimer’s disease [OR-32]
José Marco Contelles, Francisco López-Muñoz
Wednesday, 11:35 am — 11:55 am
(4539) Discovery of novel BChE inhibitors for cognitive improvement [OR-33]
Baichen Xiong, Yuanyuan Wang, Weiting Zhang, Haopeng Sun
Wednesday, 11:55 am — 12:15 pm
(4154) Development of dual pharmacophore models of acetylcholinesterase and human soluble epoxide hydrolase based on local co-solvent molecules distribution [OR-34]
Weronika Bagrowska, Artur Góra
Wednesday, 12:15 pm — 12:25 pm
(4406) Pleiotropic prodrugs for both symptomatic and disease-modifying treatment of Alzheimer’s disease [OR-35]
Anže Meden, Neža Žnidaršič, Damijan Knez, Yuanyuan Wang, Ziwei Xu, Huajing Yang, Weiting Zhang, Anja Pišlar, Andrej Perdih, Simona Kranjc Brezar, Neža Grgurevič, Stane Pajk, Haopeng Sun, Stanislav Gobec
Wednesday, 12:25 pm — 12:35 pm

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Track: Wednesday - Afternoon Lectures

Session: Session VIII - Functions of cholinesterases in different tissues

Scheduled for: Wednesday, Sep 18, 2024 2:00 pm — 4:00 pm (Europe/Ljubljana)
Chair: Karl Wah-Keung Tsim

Presentations:

(4427) Acetylcholinesterase regulates inflammatory responses and pigmentation in skin epidermis [KN-08]
Karl Wah-Keung Tsim
Wednesday, 2:00 pm — 2:30 pm
(4354) Characterizing Cardiac and Vascular Cholinesterases: From Molecular Insights to Therapeutic Prospects [OR-36]
Dominika Dingová, Kristína Szmicseková, Matej Kučera, Lenka Bies Pivačková, Tibor Hodbod, Parsa Shafieikazerooni, Peter Křenek, Eric Krejci, Anna Hrabovska
Wednesday, 2:30 pm — 2:50 pm
(4494) Mice with inactive cholinesterases: new tools to evaluate cholinergic and non-cholinergic functions of AChE [OR-37]
Eric Krejci
Wednesday, 2:50 pm — 3:10 pm
(4405) New perspectives on the effects of dioxin-like pollutants on acetylcholinesterase [OR-38]
Heidi QH Xie, Guanglei Yang, Ruihong Zhu, Jiahui An, Yangsheng Chen, Li Xu, Bin Zhao
Wednesday, 3:10 pm — 3:30 pm
(4630) The cholinergic enigma of pigmented and Müller glial cells [OR-39]
Paul G. Layer, Gesine Bachmann, Alex Bausch, Nicola Coronato, Gopenath Thangaraj
Wednesday, 3:30 pm — 3:50 pm
(4395) Acetylcholinesterase Reliefs Beta-Amyloid Plaque Burden via Enhancing Glial Activation in the Brain of 5×FAD Mouse [OR-40]
Yingjie Xia, Xiaoyang Wang, Maggie Suisui Guo, Ran Duan, Tingxia Dong, Karl Wah-Keung Tsim
Wednesday, 3:50 pm — 4:00 pm

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Track: Wednesday - Memorial Lecture

Session: Plenary and other Distinguished Lectures

Scheduled for: Wednesday, Sep 18, 2024 4:00 pm — 4:30 pm (Europe/Ljubljana)
Chair: Eugenio Vilanova

Presentations:

(4711) Memorial Lecture [PL-3]
Eugenio Vilanova
Wednesday, 4:00 pm — 4:25 pm

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Track: Wednesday - Closing Lecture

Session: Plenary and other Distinguished Lectures

Scheduled for: Wednesday, Sep 18, 2024 4:30 pm — 5:15 pm (Europe/Ljubljana)
Chair: Jure Stojan

Presentations:

(4511) Structural Characterization of Orphan and Taxonomically Restricted Proteins [PL-4]
Israel Silman
Wednesday, 4:30 pm — 5:15 pm

Icon legend:
– Submitting author, – Presenting author, – Corresponding author

Back to Calendar

 

Track: Wednesday - Best Poster Awards

Session: N/A

Scheduled for: Wednesday, Sep 18, 2024 5:15 pm — 5:30 pm (Europe/Ljubljana)

Back to Calendar

 

Track: Wednesday - Closing Remarks

Session: N/A

Scheduled for: Wednesday, Sep 18, 2024 5:30 pm — 5:45 pm (Europe/Ljubljana)

Back to Calendar

2016-2017 © SOCIETY.SI Event Management System